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Practice Current: How Do You Diagnose Small Fiber Neuropathy?

Introduction




Practice Current features anonymous surveys intended to assess real-life practice patterns in scenarios where uncertainty exists. There are no right or wrong answers and we understand that extra-medical factors affect neurologic practice.

Please answer each question based on your REGULAR practice, and not your IDEAL practice. For example, if “option A” would be your ideal choice but you regularly do “option B” due to encountered barriers, then choose “option B”.

Estimated Time: 4 Minutes

Case 1. A 62-year-old man with hyperlipidemia, central obesity, and well-controlled diabetes presents with bothersome dysesthesias and pain on the bottom of his feet for the last two years. Neurologic examination shows normal reflexes and vibratory sensation throughout, with some hypersensitivity when lightly brushing the feet.
1. Small fiber neuropathy can be confidently diagnosed through history and physical exam. *This question is required.
2. Which of the following tests would you typically order at the first visit? [Select all that apply.] *This question is required.
Which additional tests would you order? [Select all that apply.]  *This question is required.
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Electrodiagnostic evaluation including nerve conduction studies and electromyography is normal. A skin punch biopsy is ordered to evaluate epidermal nerve fiber density.
3. How often do you order skin biopsy for the diagnosis of small fiber neuropathy? [Choose one.] *This question is required.
What are the reasons you never order a skin biopsy? [Select all that apply.] *This question is required.
How commonly do you order a skin biopsy in patients with high suspicion of small fiber neuropathy? *This question is required.
How commonly do you order a skin biopsy in a patient with low suspicion of small fiber neuropathy? *This question is required.
In your opinion, what is the highest diagnostic value of skin biopsy? [Rank 1-4, with 1 being the most useful indication] *This question is required. Note: for the following table each column is restricted to a single answer across all rows.
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How confident are you in the accuracy of the results of a positive skin biopsy? [Select one.] *This question is required.
How confident are you in the accuracy of the results of a negative skin biopsy? [Select one.] *This question is required.
Do you perform or interpret skin biopsies for small fiber neuropathy diagnosis? *This question is required.